Background: We examined the effectiveness of the systemic cryotherapy in terms of the temperature and duration of the therapeutic series measured by oxidative stress markers in the rat animal model.
Methods: Antioxidants in serum, plasma, liver, and erythrocytes were evaluated in two study groups following 1 min exposure to – 60°C and – 90°C, for 5 and 10 days.
Results: Superoxide dismutase activity in the tissues was lower than in the serum. The glutathione peroxidase was significantly higher in – 60°C than in – 90°C, in both 5 and 10 days of exposition. The liver catalase CAT were significantly lower in – 60°C when compared to – 90°C for 5 and 10 sessions of exposure. In all analysed tissues, the sessions of cryotherapy, – 60/5 and – 60/10, were more effective in reduction malondialdehyde than sessions of – 90/5 and – 90/10. The highest total antioxidant capacity was observed in the – 60/5 group.
Conclusions: Whole body cryotherapy based on temperature – 60°C may be considered as more beneficial than – 90°C for most of the oxidative stress (OS) markers measured in the selected tissues. The temp. – 60°C is more beneficial than – 90°C when measured by activity of Total SOD, CAT, and GPx. The therapeutic sessions – 60/10 and – 60/5 were the optimal schemes of WBC model in terms of TAC and MDA amount.
Full Article : https://pubmed.ncbi.nlm.nih.gov/31223612/